Upstate New York Vacations from $450

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Your Upstate New York Vacation

Leave all the planning to us with a Upstate New York vacation package. With everything arranged before you depart, all you'll have to do is sit back, chill out and enjoy this destination's wonders to the fullest. With so much to explore on a trip to Upstate New York, it can be difficult to know where to start. Kick off your travels in Buffalo at Walden Galleria Mall and Highmark Stadium — two much-loved attractions here. Another great city to add to your itinerary is Rochester. Be sure not to miss Strong and Seabreeze Amusement Park. Expedia is your one-stop shop when it comes to planning your Upstate New York vacation. From hotels and flights, to car rentals and more, we know how to curate a travel experience like no other.

The Latest Upstate New York vacation packages

Price found within the past 48 hours. Click for updated prices.
The Inn At Fox Hollow Hotel
Sound View Greenport
The Harbor Front Inn
Harpoon House
Park Lane New York
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Where to stay in Upstate New York

Find the best Upstate New York areas and neighborhoods for the activities you enjoy most. Learn more about Upstate New York

Discover the most popular places to visit in Upstate New York

Upstate New York Hotel Deals

M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave, Buffalo, NY
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $113 total per night from Aug 13 to Aug 14
$113 total
Aug 13 - Aug 14
Total includes taxes and fees
7.2/10 Good! (1,892 reviews)
A little warm & in need of some upgrades
"Super reasonably priced. Bed was comfy enough. We were on the 6th floor and even though the AC was set to 60, it definitely was NOT 60 in our room. The shower definitely needs an upgrade. Very old & little to no water pressure."

Reviewed on Aug 8, 2025

M Hotel Buffalo
Seneca Niagara Resort & Casino

Seneca Niagara Resort & Casino

4 out of 5
310 4th St, Niagara Falls, NY
$244 nightly
The price is $244 total per night from Sep 1 to Sep 2
$244 total
Sep 1 - Sep 2
Total includes taxes and fees
8.6/10 Excellent! (3,374 reviews)
"Nice place, staff helpful. At check in was told it could be 3 hours before our room was ready. This did not end up occurring but after a long drive to hotel to be told of possible 3 hour wait for room was not what I wanted to hear."

Reviewed on Aug 11, 2025

Seneca Niagara Resort & Casino
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza, Buffalo, NY
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $153 total per night from Sep 1 to Sep 2
$153 total
Sep 1 - Sep 2
Total includes taxes and fees
7.8/10 Good! (1,468 reviews)
"The bed was super comfortable, and the service was great"

Reviewed on Aug 11, 2025

Hyatt Regency Buffalo / Hotel and Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.