Upstate New York Vacations from $390

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Your Upstate New York Vacation

Leave all the planning to us with a Upstate New York vacation package. With everything arranged before you depart, all you'll have to do is sit back, chill out and enjoy this destination's wonders to the fullest. With so much to explore on a trip to Upstate New York, it can be difficult to know where to start. Kick off your travels in Buffalo at Walden Galleria Mall and Highmark Stadium — two much-loved attractions here. Another great city to add to your itinerary is Rochester. Be sure not to miss Strong and Seabreeze Amusement Park. Expedia is your one-stop shop when it comes to planning your Upstate New York vacation. From hotels and flights, to car rentals and more, we know how to curate a travel experience like no other.

The Latest Upstate New York vacation packages

Price found within the past 48 hours. Click for updated prices.
Windrose On Hudson
Prospect Berkshires
The Inn At Fox Hollow Hotel
1 Hotel Brooklyn Bridge
Sound View Greenport
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Where to stay in Upstate New York

Find the best Upstate New York areas and neighborhoods for the activities you enjoy most. Learn more about Upstate New York

Discover the most popular places to visit in Upstate New York

Upstate New York Hotel Deals

M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave, Buffalo, NY
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $125 total per night from Aug 24 to Aug 25
$125 total
Aug 24 - Aug 25
Total with taxes and fees
7.2/10 Good! (2,007 reviews)
"Air Port"

Reviewed on Aug 23, 2025

M Hotel Buffalo
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St, Buffalo, NY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $153 total per night from Sep 8 to Sep 9
$153 total
Sep 8 - Sep 9
Total with taxes and fees
7.8/10 Good! (2,605 reviews)
"Easy checkin. Adequate parking. Quiet."

Reviewed on Aug 21, 2025

Buffalo Airport Hotel
Seneca Niagara Resort & Casino

Seneca Niagara Resort & Casino

4 out of 5
310 4th St, Niagara Falls, NY
$244 nightly
The price is $244 total per night from Sep 1 to Sep 2
$244 total
Sep 1 - Sep 2
Total with taxes and fees
8.6/10 Excellent! (3,551 reviews)
"Casino"

Reviewed on Aug 22, 2025

Seneca Niagara Resort & Casino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.